Description

Spiro[2.2]Pentanecarboxaldehyde, 4-Butyl-, (1R,3S,4R)-Rel- (9Ci) is a high-value, stereochemically defined spirocyclic aldehyde building block. Its unique, rigid three-dimensional structure makes it a critical intermediate for the synthesis of complex molecules in advanced research and development. This compound is primarily sought after by pharmaceutical and agrochemical R&D teams for applications in medicinal chemistry, asymmetric synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in programs targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the creation of novel, stereospecific herbicides, fungicides, and insecticides where the spirocyclic core can enhance biological activity and environmental profile.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of sophisticated chiral ligands and organocatalysts used in enantioselective transformations.
• Material Science Research: Employed in the development of advanced organic materials, such as liquid crystals or polymers with specific stereochemical properties.
• Academic & Contract Research: A valuable tool for synthetic organic chemists in universities and CROs exploring new methodologies and complex natural product synthesis.

Basic Information

Product Name	Spiro[2.2]Pentanecarboxaldehyde, 4-Butyl-, (1R,3S,4R)-Rel- (9Ci)
CAS No.	405873-84-9
Molecular Formula	C10H16O
Molecular Weight	152.23 g/mol
Synonyms	(1R,3S,4R)-rel-4-Butylspiro[2.2]pentane-1-carbaldehyde; 4-Butylspiro[2.2]pentane-1-carboxaldehyde, (1R,3S,4R)-rel-; rel-(1R,3S,4R)-4-Butylspiro[2.2]pentanecarbaldehyde; (1R,3S,4R)-4-Butylspiro[2.2]pentanecarboxaldehyde; Spiro[2.2]pentanecarboxaldehyde, 4-butyl-, (1R,3S,4R)-rel-
EINECS	Contact for details

Quality Control

Every batch of Spiro[2.2]Pentanecarboxaldehyde, 4-Butyl-, (1R,3S,4R)-Rel- (9Ci) is produced and controlled under a strict quality management system. We employ advanced analytical techniques, including chiral HPLC, GC, NMR, and MS, to ensure identity, purity, and enantiomeric/excess specifications are met. A comprehensive Certificate of Analysis (COA) detailing all critical parameters is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.