Description

2-Iodo-4-(Trifluoromethoxy)Phenol is a specialized halogenated phenolic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both iodine and a trifluoromethoxy substituent, makes it a valuable intermediate for creating complex molecules with tailored electronic and steric properties. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing next-generation active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Building block for creating functionalized polymers and advanced organic electronic materials due to its halogenated aromatic core.
• Custom Synthesis and R&D: Employed in contract research organizations (CROs) and academic labs for method development and exploring new chemical spaces.

Basic Information

Product Name	2-Iodo-4-(Trifluoromethoxy)Phenol
CAS No.	405517-54-6
Molecular Formula	C7H4F3IO2
Molecular Weight	303.01 g/mol
Synonyms	4-(Trifluoromethoxy)-2-iodophenol; 2-Iodo-4-(trifluoromethoxy)phenol; Phenol, 2-iodo-4-(trifluoromethoxy)-; 2-Iodo-4-trifluoromethoxyphenol; 2-Iodo-α,α,α-trifluoro-p-cresol ether
EINECS	Contact for details

Quality Control

Our 2-Iodo-4-(Trifluoromethoxy)Phenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.