Description

3-(5-Carboxy-2H-Benzotriazol-2-Yl)-L- is a specialized benzotriazole derivative, a high-value building block in advanced organic synthesis. This compound matters for its role as a key chiral intermediate, enabling the development of complex molecules with specific stereochemistry. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• As a chiral intermediate in the synthesis of pharmaceutical candidates, particularly protease inhibitors and other biologically active molecules.
• Utilized in asymmetric synthesis for constructing complex molecular architectures with high enantiomeric purity.
• Research and development of novel agrochemicals, where its benzotriazole moiety can impart specific biological activity.
• Building block for custom ligands and catalysts used in metal-organic chemistry and catalysis.
• Intermediate in the production of advanced materials, such as polymers with specific light-absorbing or stabilizing properties.
• Reference standard for analytical method development and quality control in chemical manufacturing.

Basic Information

Product Name	3-(5-Carboxy-2H-Benzotriazol-2-Yl)-L-
CAS No.	405150-18-7
Molecular Formula	C9H7N3O2
Molecular Weight	189.17 g/mol
Synonyms	L-3-(5-Carboxy-2H-benzotriazol-2-yl)alanine; (2S)-2-[3-(5-Carboxy-1H-1,2,3-benzotriazol-1-yl)]propanoic acid; 3-(5-Carboxy-1H-benzotriazol-1-yl)-L-alanine; 405150-18-7; 3-(5-Carboxy-2H-1,2,3-benzotriazol-2-yl)-L-alanine; Benzotriazole-5-carboxylic acid, 2-[(1S)-1-carboxyethyl]-; 1H-Benzotriazole-5-carboxylic acid, 1-[(1S)-1-carboxyethyl]-
EINECS	Contact for details

Quality Control

Our 3-(5-Carboxy-2H-Benzotriazol-2-Yl)-L- is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), chiral purity, and impurity profiles are available upon request, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.