Description

Benzeneacetic Acid, 4-Butyl--α--Methyl-, (-α-S)- (9Ci) CAS NO 404354-76-3 is a high-purity, chiral organic compound characterized by its specific stereochemistry at the alpha carbon. This compound is a critical chiral intermediate in the synthesis of advanced pharmaceutical ingredients, where its defined stereochemistry is essential for biological activity. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing enantiomerically pure active compounds.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring high stereoselectivity.
• Agrochemical Synthesis: Used in the research and development of chiral pesticides and herbicides, where the specific stereoisomer can influence efficacy and environmental impact.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in academic and industrial research focused on developing new asymmetric synthetic methodologies.
• Fine Chemical Production: Employed in the manufacture of other high-value, complex chiral molecules for various specialty chemical applications.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation in chiral separation techniques like HPLC.

Basic Information

Item	Details
Product Name	Benzeneacetic Acid, 4-Butyl--α--Methyl-, (-α-S)- (9Ci)
CAS No.	404354-76-3
Molecular Formula	C13H18O2
Molecular Weight	206.28 g/mol
Synonyms	(S)-2-(4-Butylphenyl)propanoic acid; (αS)-4-Butyl-α-methylbenzeneacetic acid; (-)-(S)-2-(4-Butylphenyl)propionic acid; (S)-2-(p-Butylphenyl)propanoic acid; (S)-Naproxen Impurity; (S)-4-Butyl-α-methylphenylacetic acid; (9CI) Benzeneacetic acid, 4-butyl-α-methyl-, (αS)-
EINECS	Contact for details

Quality Control

Our Benzeneacetic Acid, 4-Butyl--α--Methyl-, (-α-S)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profile is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which could affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.