Description

(R)-(+)-1-(4-Methylphenyl)Ethylamine Hydrochloride is a high-purity chiral amine salt, serving as a critical chiral building block and resolving agent in advanced organic synthesis. Its enantiomeric purity is essential for producing optically active compounds with high stereoselectivity, directly impacting the efficacy and safety of final products. This compound is primarily required by pharmaceutical R&D laboratories, agrochemical manufacturers, and fine chemical producers engaged in asymmetric synthesis and chiral resolution processes.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drugs.
• Chiral Resolving Agent: Used for the optical resolution of racemic mixtures of carboxylic acids and other acidic compounds via diastereomeric salt formation.
• Asymmetric Catalyst Ligand Precursor: Serves as a precursor for synthesizing chiral ligands used in metal-catalyzed asymmetric reactions (e.g., hydrogenation, alkylation).
• Agrochemical Synthesis: Building block for creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical & Specialty Material Production: Employed in the synthesis of liquid crystals, advanced polymers, and other performance materials requiring specific chirality.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and process chemistry research.

Basic Information

Product Name	(R)-(+)-1-(4-Methylphenyl)Ethylamine Hydrochloride
CAS No.	404336-49-8
Molecular Formula	C9H14ClN
Molecular Weight	171.67 g/mol
Synonyms	(R)-(+)-1-(p-Tolyl)ethylamine hydrochloride; (R)-1-(4-Methylphenyl)ethanamine hydrochloride; (R)-α-Methyl-4-methylbenzylamine hydrochloride; (R)-1-(4-Methylphenyl)ethylammonium chloride; (R)-p-Methyl-α-methylbenzylamine hydrochloride; Dextro-1-(p-tolyl)ethylamine hydrochloride; (R)-4-Methyl-α-methylbenzylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-(+)-1-(4-Methylphenyl)Ethylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay by HPLC, to ensure it meets stringent specifications for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the original container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (ee)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.