Description

4-Chloro-6-Cyano-Quinoline-3-Carboxylic Acid Ethyl Ester is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique molecular structure, featuring both chloro and cyano substituents on the quinoline core, makes it a critical intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in developing kinase inhibitors, anticancer agents, and other biologically active heterocyclic compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the quinoline scaffold contributes to biological activity.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Dye and Pigment Chemistry: Acts as an intermediate in the development of specialized quinoline-based dyes and functional colorants.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic chemistry and cross-coupling reactions.

Basic Information

Product Name	4-Chloro-6-Cyano-Quinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	403841-76-9
Molecular Formula	C₁₃H₉ClN₂O₂
Molecular Weight	260.68 g/mol
Synonyms	Ethyl 4-Chloro-6-cyanoquinoline-3-carboxylate; 4-Chloro-6-cyano-3-quinolinecarboxylic Acid Ethyl Ester; 3-Quinolinecarboxylic acid, 4-chloro-6-cyano-, ethyl ester; 403841-76-9; Ethyl 4-chloro-6-cyanoquinoline-3-carboxylate; 4-Chloro-6-cyanoquinoline-3-carboxylic acid ethyl ester; 6-Cyano-4-chloroquinoline-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-6-Cyano-Quinoline-3-Carboxylic Acid Ethyl Ester adheres to stringent in-process controls and final batch testing to ensure consistent high purity and reliable performance in your synthesis. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality management systems and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.