Description

(2R)-N1,N1-Dimethyl-1,2-Propanediamine 2Hcl CAS NO 403712-75-4 is a high-purity chiral diamine hydrochloride salt, serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules with precise spatial orientation. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries who require enantiomerically pure intermediates for drug discovery, process development, and the synthesis of chiral ligands or catalysts.

Application

• Pharmaceutical Intermediate: Key chiral precursor for the synthesis of active pharmaceutical ingredients (APIs), particularly in neurological and cardiovascular drug candidates.
• Asymmetric Catalyst Ligand Synthesis: Used to construct chiral ligands for transition metal catalysts in enantioselective reactions.
• Peptidomimetics Research: Serves as a constrained diamine backbone in the design and synthesis of peptide analogs and mimetics.
• Chemical Biology Probes: Employed in the development of molecular probes and tools for studying biological systems.
• Fine Chemical Synthesis: A versatile chiral synthon for creating specialty chemicals, agrochemicals, and advanced materials.
• Academic & R&D: Fundamental building block in organic chemistry research for methodological development and novel compound libraries.

Basic Information

Item	Detail
Product Name	(2R)-N1,N1-Dimethyl-1,2-Propanediamine 2Hcl
CAS No.	403712-75-4
Molecular Formula	C5H16Cl2N2
Molecular Weight	175.10 g/mol
Synonyms	(2R)-1,2-Diamino-N,N-dimethylpropane dihydrochloride; (R)-N1,N1-Dimethyl-1,2-propanediamine dihydrochloride; (R)-1,2-Diamino-N,N-dimethylpropane dihydrochloride; (R)-N,N-Dimethyl-1,2-diaminopropane dihydrochloride; (2R)-N,N-Dimethyl-1,2-propanediamine 2HCl; (R)-DMAPDA·2HCl; (R)-1,2-Propanediamine, N1,N1-dimethyl-, dihydrochloride
EINECS	Contact for details

Quality Control

Our (2R)-N1,N1-Dimethyl-1,2-Propanediamine 2Hcl is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting research and pharmaceutical-grade standards. A detailed Certificate of Analysis (COA) providing specifications for identity, assay, chiral purity, and impurities is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.