Description

2-Bromo-6-(Trifluoromethoxy)Benzoic Acid is a high-value, multi-functional aromatic building block featuring both bromine and trifluoromethoxy substituents, offering unique reactivity and physicochemical properties for advanced synthesis. This compound is critical for medicinal chemistry and agrochemical research, where its structure is leveraged to modulate bioactivity, metabolic stability, and lipophilicity in target molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in cross-coupling reactions and organometallic catalysis.
• Material Science Research: Employed in the creation of novel organic electronic materials, liquid crystals, and polymers requiring halogenated aromatic components.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences sector, enabling the production of bespoke, patent-protected compounds.

Basic Information

Product Name	2-Bromo-6-(Trifluoromethoxy)Benzoic Acid
CAS No.	403646-46-8
Molecular Formula	C8H4BrF3O3
Molecular Weight	285.02 g/mol
Synonyms	2-Bromo-6-(trifluoromethoxy)benzoic acid; Benzoic acid, 2-bromo-6-(trifluoromethoxy)-; 6-Bromo-2-(trifluoromethoxy)benzoic acid; 2-Bromo-α,α,α-trifluoro-o-anisic acid; 2-Bromo-6-trifluoromethoxybenzoic acid; 2-Br-6-OCF3-BA; BA-6-OCF3-2-Br
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-6-(Trifluoromethoxy)Benzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up activities. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and IR are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. The container must be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.