Description

Oxirane, 2-(1-Methylethyl)-2-Phenyl-, (+)- (9Ci) is a high-purity, chiral epoxide compound, also known as (+)-2-Isopropyl-2-phenylethylene oxide. This optically active intermediate is valued for its role in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce stereochemical complexity into their target molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and catalysts used in homogeneous catalysis and asymmetric transformations.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Polymer Modification: Can be used to introduce reactive epoxide and chiral phenyl-isopropyl groups into polymer chains for advanced material properties.
• Academic and Industrial R&D: A valuable reagent for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Product Name	Oxirane, 2-(1-Methylethyl)-2-Phenyl-, (+)- (9Ci)
CAS No.	403501-36-0
Molecular Formula	C11H14O
Molecular Weight	162.23 g/mol
Synonyms	(+)-2-Isopropyl-2-phenylethylene oxide; (+)-2-Phenyl-2-isopropylethylene oxide; (+)-α-Isopropyl-α-phenylethylene oxide; (R)-2-Isopropyl-2-phenylethylene oxide; (R)-2-Phenyl-2-isopropylethylene oxide; (R)-α-Isopropyl-α-phenylethylene oxide; (2R)-2-Isopropyl-2-phenyloxirane; (2R)-2-Phenyl-2-isopropyloxirane
EINECS	Contact for details

Quality Control

Our Oxirane, 2-(1-Methylethyl)-2-Phenyl-, (+)- (9Ci) is produced under strict quality management systems. Each batch is characterized and tested to ensure high enantiomeric excess (ee) and chemical purity, meeting the stringent requirements for chiral intermediates. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, open flames, and strong oxidizing agents. This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.