Description

Oxirane, 2-(4-Fluorophenyl)-3-Methyl-, (2R,3S)- (9Ci) is a high-purity, stereochemically defined chiral epoxide building block of significant value in advanced organic synthesis. Its precise (2R,3S) configuration makes it a critical intermediate for constructing complex molecules with defined stereocenters, ensuring high enantiomeric purity in final products. This compound is essential for research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries, where it serves as a key precursor for active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in therapeutic areas requiring high stereochemical fidelity.
• Agrochemical Synthesis: Used in the development of enantiomerically pure pesticides and herbicides, where biological activity is often stereospecific.
• Asymmetric Catalysis Research: Serves as a standard substrate or building block for developing and testing new chiral catalysts and synthetic methodologies.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require specific three-dimensional architecture.
• Academic & Contract Research: A valuable reagent for university laboratories and CROs (Contract Research Organizations) engaged in synthetic organic chemistry projects.

Basic Information

Item	Details
Product Name	Oxirane, 2-(4-Fluorophenyl)-3-Methyl-, (2R,3S)- (9Ci)
CAS No.	403501-33-7
Molecular Formula	C9H9FO
Molecular Weight	152.17 g/mol
Synonyms	(2R,3S)-2-(4-Fluorophenyl)-3-methyloxirane; trans-2-(4-Fluorophenyl)-3-methyloxirane; (2R,3S)-2-(p-Fluorophenyl)-3-methyloxirane; 4-Fluoro-α-methylstyrene oxide (specific isomer); (2R,3S)-Epoxy-p-fluoro-α-methylstyrene; Chiral fluorophenyl methyl oxirane; (2R,3S)-1-Fluoro-4-(2-methyloxiran-2-yl)benzene
EINECS	Contact for details

Quality Control

Our production of Oxirane, 2-(4-Fluorophenyl)-3-Methyl-, (2R,3S)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric excess (ee). Quality is verified through advanced analytical techniques including chiral HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric ratio, and impurity profiles is provided with each shipment, supporting cGMP (current Good Manufacturing Practice) compliance for use in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light). Keep container tightly sealed under an inert atmosphere (e.g., nitrogen) if long-term storage is required to prevent potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.