Description

4-Piperazino-2-(Trifluoromethyl)Quinazoline is a high-value, functionalized quinazoline derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular architecture, featuring a piperazine ring and a trifluoromethyl group, makes it a versatile intermediate for developing novel compounds with targeted biological activity. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create new active ingredients and fine-tune molecular properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the bioactivity of the quinazoline core.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science Research: Investigated as a building block for advanced organic materials, such as ligands for catalysts or components in organic electronics.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	4-Piperazino-2-(Trifluoromethyl)Quinazoline
CAS No.	401567-99-5
Molecular Formula	C13H13F3N4
Molecular Weight	282.27 g/mol
Synonyms	2-(Trifluoromethyl)-4-piperazinylquinazoline; 4-(Piperazin-1-yl)-2-(trifluoromethyl)quinazoline; Quinazoline, 4-(1-piperazinyl)-2-(trifluoromethyl)-; 4-Piperazin-1-yl-2-trifluoromethyl-quinazoline; 2-Trifluoromethyl-4-piperazinoquinazoline; 401567-99-5; 4-(Piperazin-1-yl)-2-(trifluoromethyl)quinazoline
EINECS	Contact for details

Quality Control

Every batch of 4-Piperazino-2-(Trifluoromethyl)Quinazoline is produced under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.