Description

1-[6-Chloro-2-(Trifluoromethyl)Quinol-4-Yl]Piperazine is a high-value, multi-functional heterocyclic building block featuring a quinoline core substituted with chlorine, trifluoromethyl, and piperazine groups. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, where its unique structure imparts desirable biological activity and physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Key pharmaceutical intermediate in the research and development of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Building block for agrochemical active ingredients, such as herbicides and fungicides, leveraging the biological activity of the quinoline scaffold.
• Versatile precursor in organic synthesis for constructing complex heterocyclic compounds used in material science and chemical research.
• Intermediate for the development of fluorescent dyes and probes due to the photophysical properties of the quinoline structure.
• Used in academic and industrial R&D for structure-activity relationship (SAR) studies and medicinal chemistry optimization programs.

Basic Information

Product Name	1-[6-Chloro-2-(Trifluoromethyl)Quinol-4-Yl]Piperazine
CAS No.	401567-88-2
Molecular Formula	C14H13ClF3N3
Molecular Weight	315.72 g/mol
Synonyms	4-(6-Chloro-2-(trifluoromethyl)quinolin-4-yl)piperazine; 6-Chloro-2-(trifluoromethyl)-4-(1-piperazinyl)quinoline; 1-(6-Chloro-2-(trifluoromethyl)-4-quinolinyl)piperazine; 401567-88-2; 6-Chloro-2-trifluoromethyl-4-piperazinylquinoline; Quinoline, 6-chloro-2-(trifluoromethyl)-4-(1-piperazinyl)-
EINECS	Contact for details

Quality Control

Our 1-[6-Chloro-2-(Trifluoromethyl)Quinol-4-Yl]Piperazine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory filings for pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.