Description

1-[8-Fluoro-2-(Trifluoromethyl)Quinol-4-Yl] Piperazine, 97% Min. is a high-purity, fluorinated quinoline derivative piperazine compound, serving as a critical advanced pharmaceutical intermediate. Its value lies in enabling the synthesis of novel, potent drug candidates, particularly in therapeutic areas requiring high selectivity and metabolic stability. This product is essential for research and development chemists and process scale-up teams within the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective research.
• Agrochemical Research: Used in developing new generation pesticides and herbicides, leveraging the biological activity of the quinoline scaffold.
• Chemical Biology Probe Development: Serves as a core structure for creating molecular probes to study enzyme function and biological pathways.
• Material Science Precursor: Potential use in synthesizing specialty polymers or ligands for catalytic systems due to its complex, fluorinated aromatic structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic & Institutional Research: Used in universities and research institutes for medicinal chemistry programs and novel compound library generation.

Basic Information

Product Name	1-[8-Fluoro-2-(Trifluoromethyl)Quinol-4-Yl] Piperazine, 97% Min.
CAS No.	401567-86-0
Molecular Formula	C14H13F4N3
Molecular Weight	299.27 g/mol
Synonyms	4-(8-Fluoro-2-(trifluoromethyl)quinolin-4-yl)piperazine; 8-Fluoro-2-(trifluoromethyl)-4-(piperazin-1-yl)quinoline; 1-(8-Fluoro-2-(trifluoromethyl)-4-quinolyl)piperazine; 401567-86-0; 8-Fluoro-2-trifluoromethyl-4-piperazinylquinoline; FQTP; 4-Piperazinyl-8-fluoro-2-trifluoromethylquinoline
EINECS	Contact for details

Quality Control

Every batch of 1-[8-Fluoro-2-(Trifluoromethyl)Quinol-4-Yl] Piperazine is produced and tested under a strict quality management system. We ensure the product meets the specified 97% minimum purity through advanced analytical techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	97.0% Min.
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.