Description

3-[2-(Dimethylamino)Ethyl]-4-Imino-6,7-Dimethoxy-3,4-Dihydro-2(1H)-Quinazolinethione is a sophisticated heterocyclic organic compound that serves as a critical intermediate in advanced pharmaceutical research and development. Its unique quinazolinethione core, functionalized with dimethylaminoethyl and imino groups, makes it a valuable building block for synthesizing novel bioactive molecules. This high-purity intermediate is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Chemical Biology Probe Development: Used to create tool compounds for studying enzyme mechanisms and protein-ligand interactions due to its reactive thione and imino functionalities.
• Agrochemical Research: Serves as a building block for developing new active ingredients for crop protection products, leveraging its heterocyclic scaffold.
• Material Science Applications: Investigated as a monomer or additive for creating specialty polymers with unique optical or electronic properties.
• Academic & Contract Research: Essential for medicinal chemistry programs in universities and Contract Research Organizations (CROs) focused on heterocyclic chemistry.
• Process Chemistry & Scale-Up: Used in optimizing synthetic routes and developing scalable manufacturing processes for complex molecules.

Basic Information

Product Name	3-[2-(Dimethylamino)Ethyl]-4-Imino-6,7-Dimethoxy-3,4-Dihydro-2(1H)-Quinazolinethione
CAS No.	400751-59-9
Molecular Formula	C₁₄H₂₀N₄O₂S
Molecular Weight	308.40 g/mol
Synonyms	6,7-Dimethoxy-3-[2-(dimethylamino)ethyl]-4-imino-3,4-dihydro-2(1H)-quinazolinethione; 2(1H)-Quinazolinethione, 3,4-dihydro-3-[2-(dimethylamino)ethyl]-4-imino-6,7-dimethoxy-; 400751-59-9; 3-(2-Dimethylaminoethyl)-4-imino-6,7-dimethoxy-3,4-dihydroquinazoline-2-thione; 6,7-Dimethoxy-3-(2-dimethylaminoethyl)-4-imino-3,4-dihydroquinazoline-2-thiol; Quinazolinethione derivative CAS 400751-59-9
EINECS	Contact for details

Quality Control

Our 3-[2-(Dimethylamino)Ethyl]-4-Imino-6,7-Dimethoxy-3,4-Dihydro-2(1H)-Quinazolinethione is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and Mass Spectrometry, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment. We can support development toward cGMP standards as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants or storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.