Description

[(1R)-1-(Aminomethyl)-2-Phenylethyl]-Carbamic Acid Phenylmethyl Ester is a chiral, protected amino acid derivative of significant value in advanced organic synthesis. This compound serves as a crucial high-purity building block for the construction of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by pharmaceutical companies, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of peptide mimetics, active pharmaceutical ingredients (APIs), and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, including enzyme inhibitors and receptor modulators.
• Peptidomimetic Synthesis: Used as a protected amino acid derivative for constructing non-natural peptide analogs with enhanced stability and bioavailability.
• Asymmetric Synthesis: Serves as a chiral auxiliary or starting material in stereoselective chemical reactions to introduce specific stereocenters.
• API Development: Employed in the synthetic pathways for potential Active Pharmaceutical Ingredients (APIs), especially in oncology and neurology research.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Scale-up: A critical raw material for custom synthesis services, from milligram-scale research to kilogram-scale pilot production.

Basic Information

Product Name	[(1R)-1-(Aminomethyl)-2-Phenylethyl]-Carbamic Acid Phenylmethyl Ester
CAS No.	400652-48-4
Molecular Formula	C17H20N2O2
Molecular Weight	284.36 g/mol
Synonyms	N-[(1R)-1-(Aminomethyl)-2-phenylethyl]carbamic acid benzyl ester; Benzyl N-[(1R)-1-(aminomethyl)-2-phenylethyl]carbamate; (1R)-1-(Aminomethyl)-2-phenylethyl-carbamic acid benzyl ester; (R)-Benzyl (1-(aminomethyl)-2-phenylethyl)carbamate; Cbz-(R)-HomoPhe-NH2; (R)-2-Amino-3-phenylpropyl-carbamic acid benzyl ester; Benzyloxycarbonyl-(R)-homophenylalanine amide
EINECS	Contact for details

Quality Control

Our [(1R)-1-(Aminomethyl)-2-Phenylethyl]-Carbamic Acid Phenylmethyl Ester is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, chiral analysis, and NMR, to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are available upon request for quality assurance and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.