Description

(S)-Benzyl 1-Aminopropan-2-Ylcarbamate CAS NO 400652-46-2 is a high-purity chiral building block and protected amino acid derivative of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for the preparation of complex pharmaceutical molecules, particularly in the development of peptide-based therapeutics and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in the synthesis of novel drugs and bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide drugs, protease inhibitors, and other biologically active molecules.
• Peptide Chemistry: Used for the controlled introduction of the (S)-2-aminopropane moiety into peptide chains, enabling structure-activity relationship (SAR) studies.
• Asymmetric Synthesis: Serves as a valuable starting material or auxiliary in catalytic asymmetric transformations to create enantiomerically pure compounds.
• API Development: Employed in research and process development for new Active Pharmaceutical Ingredients (APIs), especially in oncology and metabolic disease research.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein-protein interactions.
• Custom Synthesis: A fundamental building block for contract research and manufacturing organizations (CROs/CMOs) offering bespoke chemical synthesis services.

Basic Information

Product Name	(S)-Benzyl 1-Aminopropan-2-Ylcarbamate
CAS No.	400652-46-2
Molecular Formula	C11H16N2O2
Molecular Weight	208.26 g/mol
Synonyms	(S)-Benzyl (1-amino-2-propanyl)carbamate; (S)-Benzyl 1-amino-2-propylcarbamate; (S)-Benzyloxycarbonyl-1,2-diaminopropane; (S)-Z-1,2-diaminopropane; (S)-Cbz-1,2-diaminopropane; (S)-Nα-Cbz-1,2-diaminopropane; (S)-1-Amino-2-(benzyloxycarbonylamino)propane; (S)-2-[(Benzyloxy)carbonyl]amino-1-aminopropane
EINECS	Contact for details

Quality Control

Our (S)-Benzyl 1-Aminopropan-2-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.