Description

2-[3-(Trifluoromethyl)Phenyl]-1,3-Thiazole-4-Carbohydrazide is a high-value heterocyclic building block and key synthetic intermediate, prized for its trifluoromethylphenyl and carbohydrazide functionalities. This compound is essential for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique structure enables the fine-tuning of biological activity and physicochemical properties. It is primarily targeted at the pharmaceutical, agrochemical, and advanced material synthesis industries for applications in medicinal chemistry and crop protection research.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly in developing kinase inhibitors, antimicrobials, and anti-inflammatory agents.
• Agrochemical Research: Serves as a key precursor for creating new-generation herbicides, fungicides, and insecticides that leverage the trifluoromethyl group for enhanced efficacy and environmental profile.
• Chemical Biology & Proteomics: Used in the design and synthesis of chemical probes and activity-based probes (ABPs) for target identification and validation studies.
• Material Science: Employed as a monomer or functional additive in the research of specialty polymers and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-[3-(Trifluoromethyl)Phenyl]-1,3-Thiazole-4-Carbohydrazide
CAS No.	400083-64-9
Molecular Formula	C11H8F3N3OS
Molecular Weight	287.26 g/mol
Synonyms	2-[3-(Trifluoromethyl)phenyl]-1,3-thiazole-4-carbohydrazide; 2-[3-(Trifluoromethyl)phenyl]-4-thiazolecarbohydrazide; 4-Thiazolecarboxylic acid, 2-[3-(trifluoromethyl)phenyl]-, hydrazide; 2-(3-Trifluoromethylphenyl)thiazole-4-carbohydrazide; 2-(3-(Trifluoromethyl)phenyl)thiazole-4-carbohydrazide; 400083-64-9; AKOS005158209
EINECS	Contact for details

Quality Control

Our 2-[3-(Trifluoromethyl)Phenyl]-1,3-Thiazole-4-Carbohydrazide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.