Description

α-2-Piperidyl-2,8-Bis(Trifluoromethyl)Quinoline-4-Methanol is a sophisticated, high-purity organic compound featuring a quinoline core substituted with piperidine and trifluoromethyl groups. This molecular architecture makes it a critical advanced intermediate for the synthesis of complex active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for developing next-generation products.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Serves as a precursor for developing advanced crop protection agents, including herbicides and fungicides with enhanced efficacy.
• Chemical Research & Development: Used in academic and industrial R&D for exploring new chemical entities and reaction pathways due to its unique fluorinated structure.
• Material Science Precursor: Potential application in the synthesis of specialty polymers or organic electronic materials requiring fluorinated components.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	α-2-Piperidyl-2,8-Bis(Trifluoromethyl)Quinoline-4-Methanol
CAS No.	49752-90-1
Molecular Formula	C₁₈H₁₈F₆N₂O
Molecular Weight	392.34 g/mol
Synonyms	2,8-Bis(trifluoromethyl)-4-(hydroxymethyl)-α-(2-piperidinyl)quinoline; 4-(Hydroxymethyl)-α-(2-piperidinyl)-2,8-bis(trifluoromethyl)quinoline; α-(2-Piperidyl)-2,8-bis(trifluoromethyl)-4-quinolinemethanol; Mefloquine Impurity F; WR 142,490 Metabolite; (RS)-α-2-Piperidyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol
EINECS	Contact for details

Quality Control

Our production of α-2-Piperidyl-2,8-Bis(Trifluoromethyl)Quinoline-4-Methanol adheres to stringent quality management systems. The material is manufactured and controlled to meet exacting standards for use in regulated environments. Certificates of Analysis (COA) are provided with each batch, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques including HPLC, GC, and NMR.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.