Description

4-Chloro-6-(Trifluoromethyl)Quinoline is a high-value, halogenated quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both chloro and trifluoromethyl substituents, provides exceptional reactivity and physicochemical properties for creating complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in the development of kinase inhibitors, antiviral agents, and other biologically active molecules.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can enhance metabolic stability and bioavailability.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs or charge-transport materials, due to the electron-withdrawing nature of its substituents.
• Ligand and Catalyst Development: Serves as a sophisticated backbone for creating novel ligands in coordination chemistry and catalysis.
• Fluorine Chemistry Studies: An important compound for investigating structure-activity relationships (SAR) in fluorine-containing molecules.

Basic Information

Product Name	4-Chloro-6-(Trifluoromethyl)Quinoline
CAS No.	49713-56-6
Molecular Formula	C10H5ClF3N
Molecular Weight	231.60 g/mol
Synonyms	6-Trifluoromethyl-4-chloroquinoline; 4-Chloro-6-(trifluoromethyl)quinoline; Quinoline, 4-chloro-6-(trifluoromethyl)-; 4-Chloro-6-trifluoromethylquinoline; 4-Chloro-6-trifluoromethyl-quinoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-(Trifluoromethyl)Quinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP standards for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.