Description

6-(Trifluoromethyl)Quinolin-4-Ol is a high-purity fluorinated quinoline derivative, a key advanced intermediate in modern synthetic chemistry. Its value lies in the unique reactivity and stability imparted by the trifluoromethyl group, making it indispensable for constructing complex molecular architectures. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a starting material for creating specialized ligands, catalysts, and functional organic molecules used in advanced materials.
• Chemical Synthesis: Employed in organic synthesis for introducing the quinoline scaffold and the CF3 moiety into more complex molecules via various coupling and functionalization reactions.
• Academic & Industrial R&D: A valuable reagent for research institutions and corporate R&D departments exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	6-(Trifluoromethyl)Quinolin-4-Ol
CAS No.	49713-51-1
Molecular Formula	C10H6F3NO
Molecular Weight	213.16 g/mol
Synonyms	4-Hydroxy-6-(trifluoromethyl)quinoline; 6-(Trifluoromethyl)-4-quinolinol; 6-Trifluoromethylquinolin-4-ol; 4-Quinolinol, 6-(trifluoromethyl)-; 6-Trifluoromethyl-4-hydroxyquinoline; Quinolin-4-ol, 6-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 6-(Trifluoromethyl)Quinolin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our standard material meets high-purity research grade specifications, suitable for demanding synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is sensitive to strong alkalis and fluorides; keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.