Description

2,4,6,8-Tetramethylquinoline is a substituted quinoline derivative characterized by its four methyl groups at the 2, 4, 6, and 8 positions of the quinoline ring system. This specific alkylation pattern makes it a valuable intermediate and building block in advanced organic synthesis, particularly for creating complex heterocyclic compounds. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring tailored molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the quinoline core contributes to biological activity.
• Ligand and Catalyst Development: Acts as a starting material for creating nitrogen-containing ligands used in transition metal catalysis for fine chemical production.
• Organic Light-Emitting Diodes (OLEDs): Investigated as a potential electron-transporting or host material in the construction of organic electronic devices.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized quinoline-based dyes and colorants for high-performance applications.
• Corrosion Inhibitor Formulation: Incorporated into formulations designed to protect metals in harsh industrial environments.
• Research & Development: Employed in academic and industrial labs for methodological studies and the exploration of new chemical reactions.

Basic Information

Product Name	2,4,6,8-Tetramethylquinoline
CAS No.	49616-71-9
Molecular Formula	C13H15N
Molecular Weight	185.27 g/mol
Synonyms	2,4,6,8-Tetramethylquinoline; Quinoline, 2,4,6,8-tetramethyl-; 2,4,6,8-Tetramethyl-chinolin; NSC 406914; 2,4,6,8-TMQ
EINECS	256-400-5

Quality Control

Our 2,4,6,8-Tetramethylquinoline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.