Description

Spiro[7-Azabicyclo[4.1.0]Heptane-2,2-[1,3]Dioxolane] (9Ci) is a specialized spirocyclic organic compound featuring a fused azabicycloheptane and dioxolane ring system, serving as a versatile and high-value synthetic building block. Its unique, rigid three-dimensional structure makes it a critical intermediate for constructing complex molecules in advanced pharmaceutical research and fine chemical synthesis. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides with complex stereochemistry.
• Chiral Auxiliary/ Ligand Precursor: The spirocyclic structure can be utilized to develop chiral catalysts or ligands for asymmetric synthesis.
• Material Science Research: Serves as a monomer or precursor for creating polymers with specific rigid backbones or for advanced organic electronic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and exploring new chemical spaces.
• Peptidomimetics & Bioisosteres: The fused ring system can mimic peptide turns or serve as a bioisostere in medicinal chemistry programs.

Basic Information

Product Name	Spiro[7-Azabicyclo[4.1.0]Heptane-2,2-[1,3]Dioxolane] (9Ci)
CAS No.	49613-86-7
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	7-Azabicyclo[4.1.0]heptane, spiro[2,2] with 1,3-dioxolane (9CI); 1-Oxa-4-azaspiro[4.4]nonane, 2,2-dihydro-; Spiro[1,3-dioxolane-2,2'-7-azabicyclo[4.1.0]heptane]; 2,2-Dihydro-1-oxa-4-azaspiro[4.4]nonane; Azaspiro[4.4]nonane derivative.
EINECS	Contact for details

Quality Control

Every batch of Spiro[7-Azabicyclo[4.1.0]Heptane-2,2-[1,3]Dioxolane] (9Ci) is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.