Description

(6-Trifluoromethyl-Quinolin-4-Yl)-Hydrazine is a high-value, nitrogen-containing heterocyclic building block characterized by its quinoline core and trifluoromethyl substituent. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, where its unique structure imparts desirable biological activity and metabolic stability. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in antiviral, anticancer, and anti-inflammatory research pipelines.
• Agrochemical Synthesis: Used in developing advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating novel nitrogen-based ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, dyes, and fluorescent markers due to its conjugated quinoline system.
• Chemical Biology Probes: Utilized to synthesize molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A vital building block for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	(6-Trifluoromethyl-Quinolin-4-Yl)-Hydrazine
CAS No.	49612-02-4
Molecular Formula	C₁₀H₈F₃N₃
Molecular Weight	227.19 g/mol
Synonyms	4-Hydrazinyl-6-(trifluoromethyl)quinoline; 6-(Trifluoromethyl)-4-quinolinehydrazine; (6-Trifluoromethyl-4-quinolyl)hydrazine; Quinoline, 4-hydrazinyl-6-(trifluoromethyl)-; 4-Quinolinehydrazine, 6-(trifluoromethyl)-; 6-Trifluoromethylquinolin-4-ylhydrazine; 49612-02-4 (CAS)
EINECS	Contact for details

Quality Control

Our (6-Trifluoromethyl-Quinolin-4-Yl)-Hydrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.