Description

Dl-Alanine-Obzl p-Tosylate is a protected amino acid derivative, specifically the p-toluenesulfonate salt of N-benzyloxycarbonyl-DL-alanine, serving as a crucial chiral building block in advanced organic synthesis. This compound is valued for its role in facilitating peptide coupling reactions and protecting sensitive functional groups during complex multi-step syntheses. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel peptides, active pharmaceutical ingredients (APIs), and fine chemicals.

Application

• Peptide Synthesis: A key intermediate for the controlled introduction of the alanine moiety in solid-phase and solution-phase peptide synthesis.
• Pharmaceutical Research: Used as a chiral synthon in the research and development of new therapeutic agents and active pharmaceutical ingredients (APIs).
• Bioconjugation Chemistry: Employed in the synthesis of peptide-based linkers and probes for bioconjugation and diagnostic applications.
• Fine Chemical Production: Serves as a specialized building block in the manufacture of complex, high-value fine chemicals and catalysts.
• Academic & Industrial R&D: A standard reagent in organic chemistry laboratories for methodological development and exploring new synthetic pathways.

Basic Information

Product Name	Dl-Alanine-Obzl p-Tosylate
CAS No.	46229-47-4
Molecular Formula	C18H21NO6S
Molecular Weight	379.43 g/mol
Synonyms	N-Carbobenzyloxy-DL-alanine p-Toluenesulfonate Salt; Z-DL-Ala-OH·TsOH; N-(Benzyloxycarbonyl)-DL-alanine p-Toluenesulfonic Acid Salt; Cbz-DL-Alanine p-Tosylate; DL-Alanine, N-[(phenylmethoxy)carbonyl]-, compd. with 4-methylbenzenesulfonic acid (1:1); Benzyl N-(DL-1-carboxyethyl)carbamate 4-methylbenzenesulfonate; Alanine, N-carboxy-, N-benzyl ester, DL-, p-toluenesulfonate
EINECS	Contact for details

Quality Control

Our Dl-Alanine-Obzl p-Tosylate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR), to ensure it meets exacting standards for research and production use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (DL Ratio)	~50:50 (Racemic)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.