Description

8-Fluoro-2-Methyl-Quinoline is a high-purity fluorinated quinoline derivative, a crucial building block in advanced organic synthesis. Its value lies in its unique molecular structure, which serves as a versatile scaffold for developing novel compounds with targeted biological and material properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for creating active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in developing novel pesticides, herbicides, and fungicides, where the fluorine atom and quinoline core enhance bioactivity and environmental stability.
• Material Science: Serves as a building block for organic light-emitting diodes (OLEDs), liquid crystals, and other advanced electronic materials due to its electron-transport properties.
• Chemical Synthesis: Acts as a versatile ligand in catalysis and a fundamental scaffold for constructing complex heterocyclic compounds in medicinal chemistry.
• Dye & Pigment Industry: Utilized in the synthesis of specialized fluorophores and functional dyes for analytical and imaging applications.

Basic Information

Product Name	8-Fluoro-2-Methyl-Quinoline
CAS No.	46001-36-9
Molecular Formula	C10H8FN
Molecular Weight	161.18 g/mol
Synonyms	2-Methyl-8-fluoroquinoline; 8-Fluoroquinaldine; 8-Fluoro-2-methylquinoline; Quinoline, 8-fluoro-2-methyl-; 46001-36-9; 8-Fluoro-2-methyl-1-azanaphthalene
EINECS	Contact for details

Quality Control

Our 8-Fluoro-2-Methyl-Quinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.