Description

n-(4-Iodo-Phenyl)-Guanidine is a specialized organic compound featuring a guanidine group attached to a para-iodinated phenyl ring. This unique structure makes it a valuable intermediate in advanced organic synthesis, particularly for constructing complex molecules with specific electronic and steric properties. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, receptor antagonists, and other biologically active molecules.
• Agrochemical Research: Used in the creation of new pesticides and herbicides, leveraging the iodine atom for further functionalization and the guanidine moiety for potential biological activity.
• Organic Synthesis Reagent: Serves as a versatile precursor for cross-coupling reactions (e.g., Suzuki, Sonogashira) due to the reactive aryl-iodide bond, enabling the construction of complex biaryl and conjugated systems.
• Material Science Research: Potential monomer or additive in the development of specialty polymers, liquid crystals, or organic electronic materials where the guanidine group can influence self-assembly or charge transport.
• Chemical Biology Probe: Can be utilized to develop molecular probes for studying biological processes, where the iodine atom allows for radiolabeling (with I-125) for tracking and imaging applications.

Basic Information

Product Name	n-(4-Iodo-Phenyl)-Guanidine
CAS No.	45964-99-6
Molecular Formula	C7H8IN3
Molecular Weight	261.06 g/mol
Synonyms	1-(4-Iodophenyl)guanidine; 4-Iodophenylguanidine; N-(p-Iodophenyl)guanidine; Guanidine, N-(4-iodophenyl)-; (4-Iodophenyl)guanidine; p-Iodophenylguanidine; 45964-99-6; N-(4-Iodophenyl)guanidine
EINECS	Contact for details

Quality Control

Our n-(4-Iodo-Phenyl)-Guanidine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from techniques such as HPLC, NMR, and elemental analysis. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.