Description

n-Formyl-D-Leucine, Tech. 90% is a protected derivative of the non-essential amino acid D-leucine, where the amino group is formylated. This modification is crucial for its primary role as a key chiral building block and intermediate in the synthesis of more complex peptides and pharmaceutical compounds. It is essential for research and production facilities in the pharmaceutical, biotechnology, and fine chemical sectors that require high-purity, enantiomerically pure intermediates for drug discovery and development processes.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs), particularly for peptide-based drugs and enzyme inhibitors.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis as a protected D-leucine derivative, enabling the construction of specific peptide sequences with desired stereochemistry.
• Biochemical Research: Serves as a standard or reagent in metabolic studies, enzyme-substrate interaction research, and the investigation of amino acid transport mechanisms.
• Asymmetric Catalysis: Employed as a ligand precursor or chiral auxiliary in catalytic reactions to induce stereoselectivity.
• Fine Chemical Production: A building block for manufacturing specialty chemicals, agrochemicals, and advanced materials where optical purity is paramount.
• Reference Standard: Can be utilized as a reference material in analytical laboratories for method development and quality control of related substances.

Basic Information

Product Name	n-Formyl-D-Leucine, Tech. 90%
CAS No.	44978-39-4
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	D-Leucine, N-formyl-; (R)-2-Formamido-4-methylpentanoic acid; Formyl-D-leucine; N-Formyl-D-leucine; D-(-)-N-Formylleucine; (R)-N-Formylleucine; F-D-Leu-OH; D-Leu-NH-CHO
EINECS	Contact for details

Quality Control

Our n-Formyl-D-Leucine, Tech. 90% is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral assay, to ensure it meets the declared technical specifications and is suitable for its intended synthetic applications. Certificates of Analysis (COA) documenting identity, purity, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent absorption of atmospheric moisture, which may affect product quality and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 90.0%
Chiral Purity (HPLC)	≥ 98.0% D-isomer
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.