Description

Alanine, n-(2-Hydroxy-1-Oxopropyl)- (9Ci) CAS NO 44977-66-4 is a specialized derivative of the amino acid alanine, featuring a hydroxy-oxopropyl substituent on the nitrogen. This structural modification makes it a valuable chiral building block and intermediate in advanced organic synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and fine chemical sectors for developing novel compounds, including active pharmaceutical ingredients (APIs) and complex ligands.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and metabolic pathways.
• Peptide Synthesis: Used as a modified amino acid building block in solid-phase and solution-phase peptide synthesis to introduce specific functional groups or alter peptide properties.
• Bioconjugation Chemistry: Acts as a linker or spacer molecule in the conjugation of drugs, probes, or polymers to biomolecules like proteins and antibodies.
• Catalyst Ligand Preparation: Employed in the synthesis of novel chiral ligands for asymmetric catalysis, enhancing the enantioselectivity of metal-catalyzed reactions.
• Biochemical Research: Utilized as a substrate or inhibitor in enzymatic studies to investigate metabolic pathways and enzyme mechanisms.
• Fine Chemical Synthesis: Functions as a versatile intermediate for creating complex organic molecules with potential applications in agrochemicals and material science.

Basic Information

Product Name	Alanine, n-(2-Hydroxy-1-Oxopropyl)- (9Ci)
CAS No.	44977-66-4
Molecular Formula	C6H11NO4
Molecular Weight	161.16 g/mol
Synonyms	N-(2-Hydroxy-1-oxopropyl)alanine; N-Lactoylalanine; 2-(2-Hydroxypropanamido)propanoic acid; Alanine, N-lactoyl-; N-(1-Carboxyethyl)-2-hydroxypropanamide; N-(2-Hydroxypropionyl)alanine; (2R)-2-[(2-Hydroxypropanoyl)amino]propanoic acid (for enantiomer); Alanine derivative, N-hydroxypropionyl
EINECS	Contact for details

Quality Control

Our Alanine, n-(2-Hydroxy-1-Oxopropyl)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, chiral purity, and impurity profiles. Our quality commitment supports applications requiring high-purity intermediates, including cGMP manufacturing for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent absorption of atmospheric moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (enantiomer-specific)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.