Description

Methionine, Hydrazide CAS NO 44898-03-5 is a specialized derivative of the essential amino acid methionine, featuring a reactive hydrazide functional group. This compound is valued for its role as a versatile building block and intermediate in the synthesis of more complex molecules, particularly in pharmaceutical and biochemical research. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for applications in drug discovery, peptide modification, and the development of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting metabolic pathways or requiring specific amino acid modifications.
• Bioconjugation & Peptide Chemistry: Utilized for the site-specific modification of peptides, proteins, and antibodies due to its reactive hydrazide moiety, enabling the creation of targeted drug conjugates or diagnostic probes.
• Agrochemical Research: Serves as an intermediate in the development of novel herbicides, fungicides, or plant growth regulators that incorporate modified amino acid structures.
• Biochemical Research Reagent: Employed in laboratory studies to investigate enzyme inhibition, metabolic processes, or as a standard in analytical method development.
• Cross-linking Agent: Used in material science and polymer chemistry to create cross-linked hydrogels or functionalized surfaces for biomedical applications.
• Chiral Building Block: Provides a chiral center for the asymmetric synthesis of complex organic molecules in fine chemical production.

Basic Information

Product Name	Methionine, Hydrazide
CAS No.	44898-03-5
Molecular Formula	C5H13N3O2S
Molecular Weight	179.24 g/mol
Synonyms	L-Methionine hydrazide; Methionyl hydrazide; (2S)-2-Amino-4-(methylsulfanyl)butanehydrazide; Methionine hydrazide; 2-Amino-4-(methylthio)butyric acid hydrazide; H-Met-NHNH2; L-2-Amino-4-(methylthio)butyric acid hydrazide
EINECS	Contact for details

Quality Control

Our Methionine, Hydrazide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]D20	+21.0° to +24.0° (c=1 in 1N HCl)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.