Description

5,5-Bis(Bromomethyl)-2,2-Dimethyl-1,3-Dioxane is a versatile brominated acetal derivative that serves as a critical bifunctional alkylating agent and building block in advanced organic synthesis. Its value lies in its ability to introduce two reactive bromomethyl groups in a protected, symmetrical fashion, enabling the construction of complex molecular architectures with high precision. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries who require a reliable, high-purity intermediate for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing complex drug molecules, particularly those requiring symmetrical bridging or cyclization via nucleophilic substitution reactions.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where its reactive bromine atoms facilitate the creation of potent active ingredients.
• Polymer & Material Science: Acts as a cross-linking agent or monomer precursor for creating specialty polymers, resins, and dendrimers with tailored properties.
• Organic Synthesis Reagent: A valuable reagent for constructing cyclic ethers, crown ether analogs, and other oxygen-containing heterocycles in academic and industrial R&D.
• Ligand & Catalyst Preparation: Serves as a precursor for synthesizing chelating ligands and catalyst supports used in coordination chemistry and catalysis.
• Flame Retardant Synthon: Its bromine content makes it a potential intermediate in the synthesis of brominated flame retardants for materials.

Basic Information

Product Name	5,5-Bis(Bromomethyl)-2,2-Dimethyl-1,3-Dioxane
CAS No.	43153-20-4
Molecular Formula	C8H14Br2O2
Molecular Weight	294.00 g/mol
Synonyms	2,2-Dimethyl-5,5-bis(bromomethyl)-1,3-dioxane; 1,3-Dioxane, 5,5-bis(bromomethyl)-2,2-dimethyl-; 5,5-Di(bromomethyl)-2,2-dimethyl-1,3-dioxane; NSC 169102; 2,2-Dimethyl-5,5-di(bromomethyl)-1,3-dioxane; 5,5-Bis(bromomethyl)-2,2-dimethyldioxane; Acetaldehyde, bromo-, cyclic acetal with pentaerythritol dibromide (related); Pentaerythritol dibromide cyclic acetal with bromoacetaldehyde
EINECS	Contact for details

Quality Control

Every batch of 5,5-Bis(Bromomethyl)-2,2-Dimethyl-1,3-Dioxane is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the stringent requirements for use as a pharmaceutical intermediate and in other critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature and reactive bromine groups, prolonged exposure to light, heat, or moisture should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	78 - 82 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.