Description

1 2-o-Isopropylidene-3-o-Methyl-α-D is a specialized carbohydrate derivative and a key protected sugar intermediate. This compound is crucial for synthetic chemists as it provides a versatile chiral building block with defined stereochemistry for complex molecule assembly. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of nucleosides, antiviral agents, and other fine chemicals where precise stereocontrol is essential.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the synthesis of nucleoside analogs and antiviral/antitumor agents.
• Glycochemistry Research: Used as a protected glycosyl donor or acceptor in the synthesis of complex oligosaccharides and glycoconjugates.
• Fine Chemical Synthesis: Serves as a versatile building block for the preparation of other protected sugar derivatives and specialty chemicals.
• Academic & Industrial R&D: Employed in methodological development and scale-up processes for carbohydrate-based active pharmaceutical ingredients (APIs).

Basic Information

Product Name	1 2-o-Isopropylidene-3-o-Methyl-α-D
CAS No.	43138-66-5
Molecular Formula	C10H18O5
Molecular Weight	218.25 g/mol
Synonyms	1,2-O-Isopropylidene-3-O-methyl-α-D-glucofuranose; 3-O-Methyl-1,2-O-isopropylidene-α-D-glucofuranose; 3-O-Methyl-1,2:5,6-di-O-isopropylidene-α-D-glucofuranose (precursor); 3-O-Methyl-1,2-O-(1-methylethylidene)-α-D-glucofuranose; 1,2-O-(1-Methylethylidene)-3-O-methyl-α-D-glucofuranose; 3-Methyl Ether of 1,2-O-Isopropylidene-α-D-glucofuranose; Protected 3-O-Methyl-D-glucose
EINECS	Contact for details

Quality Control

Our 1 2-o-Isopropylidene-3-o-Methyl-α-D is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, optical rotation, and identity confirmation (IR, NMR). A Certificate of Analysis (COA) is supplied with each batch, and custom synthesis to meet specific purity grades (e.g., >98%, >99%) is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	-20° to -25° (c=1 in CHCl3)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.