Description

(-)-Dob CAS NO 43061-15-0 is a chiral organic compound of significant interest in advanced chemical synthesis and pharmaceutical research. Its specific stereochemistry makes it a valuable building block for developing enantiomerically pure active pharmaceutical ingredients (APIs) and other fine chemicals. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise molecular control for their processes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly where specific enantiomeric activity is required.
• Asymmetric Synthesis: Employed as a building block or catalyst ligand in stereoselective synthesis to create complex molecules with high enantiomeric excess.
• Agrochemical Research: Used in the development of enantiomerically pure pesticides and herbicides, where one isomer often exhibits superior biological activity.
• Material Science: Potential application in the synthesis of chiral polymers or liquid crystals for advanced optical and electronic materials.
• Academic & Industrial R&D: Serves as a standard or reagent in methodological studies and process chemistry within university and corporate laboratories.

Basic Information

Product Name	(-)-Dob
CAS No.	43061-15-0
Molecular Formula	C11H17NO2
Molecular Weight	195.26 g/mol
Synonyms	(-)-4-Bromo-2,5-dimethoxyamphetamine; (R)-(-)-DOB; (R)-4-Bromo-2,5-dimethoxy-α-methylphenethylamine; Levodob; (R)-DOB; 1-(4-Bromo-2,5-dimethoxyphenyl)-2-aminopropane (R-form); (-)-2,5-Dimethoxy-4-bromoamphetamine
EINECS	Contact for details

Quality Control

Our (-)-Dob is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC, identity confirmation by IR and NMR spectroscopy, and stringent control of related substances. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.