Description

4-Bromo-3-Iodobenzoic Acid is a halogenated benzoic acid derivative that serves as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its precise molecular architecture, featuring both bromine and iodine substituents, makes it a critical building block for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors, particularly for developing active pharmaceutical ingredients (APIs), liquid crystal materials, and specialized ligands for catalysis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the halogen atoms facilitate further functionalization.
• Liquid Crystal & OLED Materials: Serves as a building block for creating halogenated aromatic cores in electronic materials for displays and lighting.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the orthogonal reactivity of the bromine and iodine groups.
• Ligand & Catalyst Development: Utilized in the preparation of specialized bidentate or polydentate ligands for transition metal catalysis.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in organic synthesis and methodology development.

Basic Information

Product Name	4-Bromo-3-Iodobenzoic Acid
CAS No.	42860-06-0
Molecular Formula	C7H4BrIO2
Molecular Weight	326.92 g/mol
Synonyms	3-Iodo-4-bromobenzoic Acid; Benzoic acid, 4-bromo-3-iodo-; 4-Bromo-3-iodo-benzoic acid; 42860-06-0; 4-Br-3-I-C6H3-COOH
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Iodobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and production. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.