Description

N'-(4-Chloro-2-Cyanophenyl)-N,n-Dimethylformamidine Monohydrochloride is a high-purity organic intermediate of significant importance in advanced chemical synthesis. This compound matters as a critical building block for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the manufacturing of advanced pesticides and herbicides, where its structural motifs contribute to biological activity.
• Chemical Research & Development: Serves as a versatile building block for constructing heterocyclic compounds and complex organic frameworks in academic and industrial labs.
• Material Science Applications: Potential use in the synthesis of organic ligands for catalysts or functional materials.
• Custom Synthesis Projects: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical production.

Basic Information

Product Name	N'-(4-Chloro-2-Cyanophenyl)-N,n-Dimethylformamidine Monohydrochloride
CAS No.	42755-45-3
Molecular Formula	C10H11ClN3·HCl
Molecular Weight	244.58 g/mol (Free base: 208.67 g/mol)
Synonyms	4-Chloro-2-((dimethylamino)methyleneamino)benzonitrile hydrochloride; N,N-Dimethyl-N'-(4-chloro-2-cyanophenyl)formamidine hydrochloride; 2-Cyano-4-chloro-N,N-dimethylformamidine hydrochloride; (4-Chloro-2-cyanophenyl)dimethylformamidine monohydrochloride; 42755-45-3; N'-(4-Chloro-2-cyanophenyl)-N,N-dimethylformamidinium chloride
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for fine chemical intermediates. We employ advanced analytical techniques, including HPLC, NMR, and mass spectrometry, to verify identity, purity, and consistency. Certificates of Analysis (COA) are provided with each batch, detailing all relevant specifications. Our quality management system is designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.