Description

Methylsulfasalazine CAS NO 42753-53-7 is a synthetic sulfonamide derivative of significant interest in pharmaceutical research and development. This compound serves as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of therapeutic agents, particularly those targeting inflammatory pathways. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of anti-inflammatory and immunosuppressive drugs.
• Research Chemical: Used in biochemical and pharmacological studies to investigate sulfonamide mechanisms and structure-activity relationships (SAR).
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• API Synthesis: Employed in the manufacturing process of salicylate-based pharmaceutical compounds.

Basic Information

Product Name	Methylsulfasalazine
CAS No.	42753-53-7
Molecular Formula	C15H14N4O5S
Molecular Weight	362.36 g/mol
Synonyms	5-[[4-[(2-Methyl-4-pyrimidinyl)amino]phenyl]azo]salicylic acid; 5-[[p-[(2-Methyl-4-pyrimidinyl)amino]phenyl]azo]salicylic acid; Methyl Sulfasalazine; Methyl Sulphasalazine; 2-Hydroxy-5-[[4-[(2-methyl-4-pyrimidinyl)amino]phenyl]azo]benzoic acid
EINECS	Contact for details

Quality Control

Our Methylsulfasalazine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.