Description

1,4-Butanediol, Monomethanesulfonate is a high-purity chemical intermediate, also known as 1,4-Butanediol monomethanesulfonate ester. This compound serves as a critical building block in advanced organic synthesis, valued for its reactivity as a mesylate ester. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and fine chemical sectors for the development of active pharmaceutical ingredients (APIs) and other specialty molecules.

Application

• Pharmaceutical Synthesis: A key intermediate in the production of various active pharmaceutical ingredients (APIs) and prodrugs.
• Fine Chemical Manufacturing: Used as a versatile alkylating agent and protecting group reagent in complex organic synthesis.
• Polymer Chemistry: Employed in the synthesis of specialized polymers and functional materials.
• Bioconjugation: Acts as a linker molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Agrochemical Research: Serves as a precursor in the synthesis of novel crop protection agents and herbicides.
• Academic & Industrial R&D: A valuable reagent for method development and exploratory chemistry in laboratory settings.

Basic Information

Product Name	1,4-Butanediol, Monomethanesulfonate
CAS No.	42729-95-3
Molecular Formula	C5H12O4S
Molecular Weight	168.21 g/mol
Synonyms	1,4-Butanediol monomethanesulfonate; 4-Hydroxybutyl methanesulfonate; 1-Methanesulfonyloxy-4-hydroxybutane; Butane-1,4-diol monomethanesulfonate; 4-(Methylsulfonyloxy)butan-1-ol; Mesyloxybutanol; 1,4-BD monomesylate; 4-Hydroxybutyl mesylate
EINECS	Contact for details

Quality Control

Our 1,4-Butanediol, Monomethanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports applications requiring GMP-grade intermediates and research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.