Description

Capsular Polysaccharide K5 is a high-purity, structurally defined polysaccharide antigen derived from specific bacterial strains. This compound is of significant value in the research and development of advanced vaccines and immunotherapies, particularly as a carrier or target antigen. It is primarily required by biotechnology and pharmaceutical companies engaged in the development of conjugate vaccines, immunological assays, and glycobiology research. Its defined structure is critical for ensuring batch-to-batch consistency and reliable experimental or production outcomes.

Application

• Conjugate Vaccine Development: Serves as a critical antigenic component or carrier polysaccharide in the formulation of bacterial vaccines.
• Immunological Research: Used as a standard or target antigen in immunoassays (ELISA, immunoblotting) to study immune responses and antibody specificity.
• Glycobiology Studies: Employed as a model compound for investigating polysaccharide biosynthesis, structure-activity relationships, and host-pathogen interactions.
• Diagnostic Reagent Production: Utilized in the manufacture of diagnostic kits for the detection of specific bacterial infections or corresponding antibodies.
• Pharmaceutical Intermediates: Acts as a key starting material for the chemical or enzymatic synthesis of more complex glycoconjugates.
• Quality Control Reference: Provides an essential standard for the quality assurance and potency testing of vaccine batches.

Basic Information

Product Name	Capsular Polysaccharide K5
CAS No.	42615-44-1
Molecular Formula	Contact for details
Molecular Weight	High Molecular Weight Polymer
Synonyms	K5 Polysaccharide; K5 Antigen; Escherichia coli K5 Capsular Polysaccharide; Poly-N-acetylheparosan; Heparosan; K5 CPS; Bacterial Polysaccharide K5
EINECS	Contact for details

Quality Control

Our Capsular Polysaccharide K5 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation, purity assessment, and quantification of key biochemical parameters, to ensure it meets the stringent requirements for pharmaceutical and research applications. Certificates of Analysis (COA) detailing specifications such as polysaccharide content, protein/nucleic acid impurities, and molecular size distribution are provided to guarantee traceability and batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, the product should be stored in a cool, dry place, ideally at controlled room temperature (15-25°C) or as specified on the label. For long-term stability, desiccants are recommended within the storage container. Avoid repeated freeze-thaw cycles if stored frozen.

Specification

Item	Specification
Appearance	White to off-white powder or fibrous solid
Identification (IR/NMR)	Conforms to standard
Assay (Polysaccharide Content)	≥ 90% (by colorimetric assay)
Protein Content	≤ 1.0% (w/w)
Nucleic Acid Content	≤ 1.0% (w/w)
Moisture Content (Loss on Drying)	≤ 8.0%
Molecular Size Distribution (SEC-HPLC)	Reported on COA
Endotoxin Level	< 10 EU/mg (or per customer requirement)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.