Description

Benzene, 1-Bromo-3-(Methoxymethoxy)- is a specialized aromatic bromo ether compound, serving as a versatile and valuable building block in advanced organic synthesis. Its molecular structure, featuring both a reactive bromine substituent and a protected methoxymethoxy (MOM) group, makes it a critical intermediate for constructing complex molecules with high precision. This chemical is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-purity intermediates for coupling reactions and functional group manipulations.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in constructing complex aromatic cores.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides that require specific halogenated aromatic ether structures.
• Material Science Research: Serves as a monomer or precursor in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An essential substrate in palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig aminations for carbon-carbon and carbon-heteroatom bond formation.
• Organic Synthesis & Process Chemistry: Employed in multi-step synthetic routes for introducing protected hydroxyl functionalities via the MOM group, which can be selectively deprotected.
• Chemical Research & Development: A valuable tool for medicinal chemistry and discovery chemistry programs exploring new chemical entities.

Basic Information

Product Name	Benzene, 1-Bromo-3-(Methoxymethoxy)-
CAS No.	42471-59-0
Molecular Formula	C9H11BrO2
Molecular Weight	231.09 g/mol
Synonyms	3-Bromo-1-(methoxymethoxy)benzene; 1-Bromo-3-(methoxymethoxy)benzene; 3-(Methoxymethoxy)bromobenzene; m-Bromo(methoxymethoxy)benzene; (3-Bromophenyl) methoxymethyl ether; MOM-protected 3-bromophenol; 3-Bromophenyl MOM ether; Benzene, bromo-3-(methoxymethoxy)-
EINECS	Contact for details

Quality Control

Our Benzene, 1-Bromo-3-(Methoxymethoxy)- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the rigorous standards expected in pharmaceutical and fine chemical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and oxidizing agents. The product is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.