Description

4-Methylthio-α-Bromoacetophenone is a specialized brominated aromatic ketone derivative, serving as a critical high-purity synthetic intermediate in advanced organic synthesis. Its core value lies in its reactive α-bromo ketone moiety, which enables efficient carbon-carbon bond formation and functional group transformations under controlled conditions. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing thioether and ketone functionalities.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Reagent: Employed in various name reactions, such as alkylation and condensation reactions, to introduce the 4-methylthiophenylacetyl group.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Can be utilized as a reactive handle for bioconjugation and the development of chemical probes.

Basic Information

Product Name	4-Methylthio-α-Bromoacetophenone
CAS No.	42445-46-5
Molecular Formula	C9H9BrOS
Molecular Weight	245.14 g/mol
Synonyms	2-Bromo-1-(4-(methylthio)phenyl)ethan-1-one; α-Bromo-4-(methylthio)acetophenone; p-(Methylthio)phenacyl bromide; 4-Methylmercaptophenacyl bromide; 1-(4-Methylthiophenyl)-2-bromoethanone; 4-Methylsulfanylphenacyl bromide; 4-Methylthiobenzoylmethyl bromide; Bromo(4-methylthiophenyl)methyl ketone
EINECS	Contact for details

Quality Control

Our 4-Methylthio-α-Bromoacetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure the container is kept tightly sealed to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.