Description

[(3-Methoxybenzyl)Oxy]Acetic Acid CAS NO 42308-51-0 is a versatile aromatic ether carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional structure, featuring both a protected phenolic ether and a reactive carboxylic acid group, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require high-purity intermediates for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring benzyl-protected phenolic scaffolds.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where its ether linkage provides metabolic stability.
• Ligand and Catalyst Preparation: Serves as a precursor for chelating ligands in asymmetric catalysis and metal complex formation.
• Polymer Modification: Functional monomer for introducing aromatic ether and carboxylic acid groups into specialty polymers to alter solubility and thermal properties.
• Fine Chemical Production: Intermediate in the multi-step synthesis of dyes, flavors, and fragrances.
• Bioconjugation Linker: Potential use in prodrug design and bioconjugation chemistry, linking active molecules via its acid group.

Basic Information

Product Name	[(3-Methoxybenzyl)Oxy]Acetic Acid
CAS No.	42308-51-0
Molecular Formula	C10H12O4
Molecular Weight	196.20 g/mol
Synonyms	(3-Methoxybenzyloxy)acetic Acid; 2-[(3-Methoxybenzyl)oxy]acetic Acid; Acetic Acid, [(3-Methoxybenzyl)oxy]-; m-Methoxybenzyloxyacetic Acid; 3-Methoxybenzyl Glycolic Acid Ether; NSC 163080; (3-Methoxy-benzyloxy)-acetic acid
EINECS	Contact for details

Quality Control

Our [(3-Methoxybenzyl)Oxy]Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.