Description

3-Amino-5-Bromobenzoic Acid is a versatile halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both an aromatic amine and a carboxylic acid group, makes it a valuable intermediate for constructing complex molecular architectures. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and plant growth regulators, leveraging the bromine atom for structural diversification.
• Ligand and Catalyst Development: Used to create specialized chelating ligands for metal catalysts in asymmetric synthesis and cross-coupling reactions.
• Dye and Pigment Manufacturing: Intermediate in the production of azo dyes and high-performance pigments, where the amino and acid groups facilitate chromophore attachment and solubility modification.
• Polymer Modification: Serves as a monomer or functionalizing agent for engineering polymers, such as polyamides and polyimides, to introduce specific chemical reactivity or adhesion properties.
• Material Science Research: Employed in the development of organic semiconductors, metal-organic frameworks (MOFs), and other functional materials due to its rigid, planar structure and dual functionality.

Basic Information

Product Name	3-Amino-5-Bromobenzoic Acid
CAS No.	42237-85-4
Molecular Formula	C7H6BrNO2
Molecular Weight	216.03 g/mol
Synonyms	5-Bromo-3-aminobenzoic Acid; 3-Amino-5-bromobenzoic acid; Benzoic acid, 3-amino-5-bromo-; 5-Bromo-anthranilic acid; 3-Carboxy-5-bromoaniline; 5-Bromo-m-aminobenzoic acid; AI3-52021; NSC 403697
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Bromobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect purity and stability. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	215 - 220 °C
Loss on Drying	≤ 1.0 %
Residue on Ignition	≤ 0.1 %
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.