Description

1-(tert-Butoxycarbonyl)-2-Phenylhydrazine is a versatile Boc-protected phenylhydrazine derivative, a crucial building block in advanced organic synthesis. Its primary value lies in providing a protected hydrazine moiety, enabling controlled reactivity in the construction of complex heterocycles and active pharmaceutical ingredients (APIs). This high-purity intermediate is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable and scalable synthetic pathways.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various nitrogen-containing heterocycles, such as pyrazoles and indoles, which are core structures in many drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require a protected phenylhydrazine functional group.
• Fine Chemical Production: Serves as a specialized reagent for constructing complex molecules in custom synthesis and material science research.
• Research & Development: A valuable tool in academic and industrial R&D labs for methodology development and exploring new chemical spaces.
• Peptide Mimetics & Conjugates: Employed in the synthesis of hydrazide-based linkers and conjugates for bioconjugation and drug delivery systems.

Basic Information

Product Name	1-(tert-Butoxycarbonyl)-2-Phenylhydrazine
CAS No.	42116-43-8
Molecular Formula	C11H16N2O2
Molecular Weight	208.26 g/mol
Synonyms	Boc-Phenylhydrazine; N-Boc-Phenylhydrazine; tert-Butyl phenylhydrazine-1-carboxylate; 2-Phenylhydrazinecarboxylic acid 1,1-dimethylethyl ester; 1-Boc-2-phenylhydrazine; N-(tert-Butoxycarbonyl)phenylhydrazine; Phenylhydrazine, N-Boc-protected
EINECS	Contact for details

Quality Control

Our 1-(tert-Butoxycarbonyl)-2-Phenylhydrazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with full batch traceability are provided to guarantee consistent quality and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.