Description

2-(Trifluoromethyl)Quinolin-5-Ol is a high-purity fluorinated quinoline derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in the unique reactivity and stability imparted by the trifluoromethyl group, enabling the development of novel compounds with enhanced properties. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and materials science industries seeking to incorporate fluorinated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms can improve metabolic stability, bioavailability, and binding affinity.
• Material Science Research: Serves as a precursor for creating novel organic electronic materials, liquid crystals, and fluorinated polymers with specific optical or electronic properties.
• Chemical Biology & Proteomics: Employed as a scaffold or labeling agent in the development of chemical probes and inhibitors for studying enzyme function and protein interactions.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized fluorinated dyes and pigments that offer improved lightfastness and color stability.

Basic Information

Product Name	2-(Trifluoromethyl)Quinolin-5-Ol
CAS No.	41958-06-9
Molecular Formula	C₁₀H₆F₃NO
Molecular Weight	213.16 g/mol
Synonyms	5-Hydroxy-2-(trifluoromethyl)quinoline; 2-(Trifluoromethyl)-5-quinolinol; 5-Quinolinol, 2-(trifluoromethyl)-; Quinolin-5-ol, 2-(trifluoromethyl)-; 2-Trifluoromethylquinolin-5-ol; 2-Trifluoromethyl-5-hydroxyquinoline; 5-Hydroxy-2-trifluoromethylquinoline
EINECS	Contact for details

Quality Control

Every batch of 2-(Trifluoromethyl)Quinolin-5-Ol is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure consistency and high purity. Our standard grade meets typical research and intermediate synthesis requirements, with comprehensive testing via HPLC, NMR, and MS. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.