Description

3-Chloro-4-Hydroxy-1-Methylquinolin-2(1H)-One is a versatile heterocyclic organic compound that serves as a critical synthetic intermediate in advanced chemical manufacturing. Its unique quinoline-based structure provides a valuable scaffold for constructing more complex molecules with targeted biological or material properties. This high-purity building block is essential for research and development laboratories and production facilities in the pharmaceutical and agrochemical sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds targeting specific enzyme pathways.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents, including herbicides and fungicides, leveraging its heterocyclic core.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a building block for electron-transport or emissive layer materials in display and lighting technologies.
• Coordination Chemistry & Ligand Synthesis: The hydroxy and carbonyl groups can be utilized to create complexing agents or metal-organic frameworks (MOFs).
• Dye and Pigment Manufacturing: Acts as an intermediate for producing specialized quinoline-based colorants and fluorescent markers.
• Academic and Industrial R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	3-Chloro-4-Hydroxy-1-Methylquinolin-2(1H)-One
CAS No.	41878-51-7
Molecular Formula	C₁₀H₈ClNO₂
Molecular Weight	209.63 g/mol
Synonyms	3-Chloro-4-hydroxy-1-methyl-2(1H)-quinolinone; 3-Chloro-4-hydroxy-1-methylquinolin-2-one; 1-Methyl-3-chloro-4-hydroxy-2-quinolone; 3-Chloro-1-methyl-4-hydroxy-2-quinolone; 2(1H)-Quinolinone, 3-chloro-4-hydroxy-1-methyl-; 3-Chloro-4-hydroxy-1-methyl-1,2-dihydroquinolin-2-one
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-4-Hydroxy-1-Methylquinolin-2(1H)-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling. Certificates of Analysis (COA) documenting identity, purity, and related substances are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.