Description

tert-Butyl (1-Hydrazinyl-1-Oxopropan-2-Yl)Carbamate is a specialized Boc-protected hydrazide derivative, serving as a crucial building block in advanced organic synthesis. Its primary value lies in its dual functionality, offering a protected amine group and a reactive hydrazide moiety, which is essential for constructing complex molecular architectures. This high-purity intermediate is particularly vital for researchers and manufacturers in the pharmaceutical and agrochemical industries, enabling the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of heterocyclic compounds and hydrazone-based drugs.
• Peptide Mimetic Synthesis: Used in the preparation of peptide analogs and mimetics, where the hydrazide group can be utilized for conjugation or cyclization reactions.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, and plant growth regulators that incorporate hydrazine functionality.
• Crosslinking Agent: Functions as a reactive intermediate in polymer chemistry for creating crosslinked materials and specialty resins.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and bioconjugates for studying biological processes and target engagement.
• Material Science: Used in the research and development of advanced organic materials and liquid crystals.

Basic Information

Product Name	tert-Butyl (1-Hydrazinyl-1-Oxopropan-2-Yl)Carbamate
CAS No.	41863-52-9
Molecular Formula	C8H17N3O3
Molecular Weight	203.24 g/mol
Synonyms	2-[(tert-Butoxycarbonyl)amino]propanehydrazide; N-(tert-Butoxycarbonyl)-L-alanine hydrazide; Boc-L-Ala-NHNH2; Boc-Ala-NHNH2; tert-Butyl (2-hydrazinyl-2-oxoethyl)carbamate (related); Nα-Boc-L-alanine hydrazide; (2S)-2-[(tert-Butoxycarbonyl)amino]propanehydrazide
EINECS	Contact for details

Quality Control

Our tert-Butyl (1-Hydrazinyl-1-Oxopropan-2-Yl)Carbamate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize exposure to moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (L-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.