Description

1-Methanesulfonyl-2-imidazolidinone is a versatile sulfonyl derivative of imidazolidinone, serving as a high-value building block in advanced organic synthesis. Its core value lies in its dual functionality, acting as both a protected amine equivalent and a reactive electrophile, which enables the construction of complex heterocyclic frameworks. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of protease inhibitors, kinase inhibitors, and other nitrogen-containing bioactive molecules.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators requiring specific heterocyclic motifs.
• Peptidomimetics Research: Serves as a constrained scaffold or protecting group analog in the design of peptide mimics for drug discovery.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for producing specialty polymers with enhanced thermal or chemical resistance.
• Chemical Biology Probes: Utilized in the synthesis of activity-based probes and molecular tags for studying enzyme function.
• Fine Chemical Production: Intermediate for manufacturing dyes, photographic chemicals, and other high-value specialty compounds.

Basic Information

Product Name	1-Methanesulfonyl-2-imidazolidinone
CAS No.	41730-79-4
Molecular Formula	C₄H₈N₂O₃S
Molecular Weight	164.18 g/mol
Synonyms	1-(Methylsulfonyl)imidazolidin-2-one; 2-Imidazolidinone, 1-(methylsulfonyl)-; Methanesulfonylimidazolidinone; N-Methanesulfonyl-2-imidazolidinone; MSI; 1-Mesyl-2-imidazolidinone; 1-(Methanesulfonyl)imidazolidin-2-one
EINECS	Contact for details

Quality Control

Our 1-Methanesulfonyl-2-imidazolidinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.