Description

(S)-5,8A-Dimethyl-3,4,8,8A-Tetrahydro-2H,7H-Naphthalene-1,6-Dione is a high-purity chiral intermediate of significant value in advanced organic synthesis. Its defined stereochemistry and functionalized decalin core make it a critical building block for the development of complex, biologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of steroids, terpenoids, and other complex natural product analogs.
• Asymmetric Synthesis: Utilized as a starting material or scaffold for constructing molecules with specific three-dimensional configurations required for drug discovery.
• Organic Chemistry Research: Employed in methodological studies for novel cyclization, oxidation, or functionalization reactions due to its rigid bicyclic structure.
• Fine Chemical Production: Acts as a building block for creating specialty chemicals used in fragrances, agrochemicals, and advanced materials.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and compound identification.

Basic Information

Product Name	(S)-5,8A-Dimethyl-3,4,8,8A-Tetrahydro-2H,7H-Naphthalene-1,6-Dione
CAS No.	41722-49-0
Molecular Formula	C12H16O2
Molecular Weight	192.26 g/mol
Synonyms	(S)-5,8a-Dimethyl-3,4,8,8a-tetrahydro-2H-naphthalene-1,6-dione; (S)-5,8a-Dimethyl-3,4,8,8a-tetrahydro-2H,7H-naphthalene-1,6-dione; (S)-5,8a-Dimethyl-1,2,3,4,8,8a-hexahydronaphthalene-1,6-dione; (S)-Decalone derivative; (S)-1,6-Dioxo-5,8a-dimethyl-1,2,3,4,8,8a-hexahydronaphthalene; (S)-5,8a-Dimethyl-3,4,8,8a-tetrahydro-1H,6H-naphthalene-1,6-dione
EINECS	Contact for details

Quality Control

Our (S)-5,8A-Dimethyl-3,4,8,8A-Tetrahydro-2H,7H-Naphthalene-1,6-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.