Description

1-(4,6-Diethoxy-1,3,5-triazin-2-yl)-1-methylpiperidinium tetrafluoroborate is a specialized organic salt, widely recognized as a highly effective coupling reagent in peptide synthesis. Its core value lies in its ability to facilitate amide bond formation with high efficiency and minimal racemization, which is critical for producing high-purity peptides. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries who require reliable and high-yielding synthetic methodologies.

Application

• Peptide Synthesis: As a key coupling reagent (often used as a substitute for HOBt/DCC-based systems) for the solid-phase and solution-phase synthesis of peptides and peptidomimetics.
• Pharmaceutical Intermediates: In the production of active pharmaceutical ingredients (APIs) where the formation of amide bonds is a critical step.
• Bioconjugation: For linking peptides to other molecules, such as dyes, polymers, or proteins, in drug delivery and diagnostic agent development.
• Organic Synthesis: As a versatile reagent for the synthesis of complex organic molecules requiring amidation reactions under mild conditions.
• Research & Development: A vital tool in academic and industrial R&D labs for exploring new synthetic routes and novel bioactive compounds.

Basic Information

Product Name	1-(4,6-Diethoxy-1,3,5-triazin-2-yl)-1-methylpiperidinium tetrafluoroborate
CAS No.	41654-51-7
Molecular Formula	C13H23BF4N5O2
Molecular Weight	368.16 g/mol
Synonyms	DMTMM Tetrafluoroborate; 1-Methyl-1-(4,6-dimethoxy-1,3,5-triazin-2-yl)piperidinium Tetrafluoroborate; 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium Tetrafluoroborate (common related compound); DMT-MM BF4; Coupling Reagent DMTMM; 2-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-1-methyl-1,2,3,4-tetrahydroisoquinolinium Tetrafluoroborate (structural variant); 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)morpholin-4-ium Tetrafluoroborate
EINECS	Contact for details

Quality Control

Our 1-(4,6-Diethoxy-1,3,5-triazin-2-yl)-1-methylpiperidinium tetrafluoroborate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance as a coupling reagent. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.