Description

(6Ar)-5,6,6A,7-Tetrahydro-1,2-Dimethoxy-6-Methyl-4H-Dibenzo[De,G]Quinolin-3-Ol is a high-purity, complex heterocyclic compound belonging to the aporphine alkaloid class, serving as a critical advanced intermediate in pharmaceutical synthesis. Its precise molecular architecture makes it an essential building block for research and development in medicinal chemistry, offering a reliable foundation for creating novel therapeutic agents. This product is primarily targeted at pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in the development of central nervous system (CNS) and other bioactive compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex aporphine alkaloids and related pharmacologically active molecules.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and the development of new drug candidates.
• Neurological Research: Serves as a starting material for compounds targeting dopamine and other neurotransmitter receptors, relevant to CNS disorder research.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for producing high-value, specialized chemicals with complex stereochemistry.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in pharmaceutical analysis.
• Academic & Institutional R&D: Fundamental material for chemical research and teaching in advanced organic chemistry and alkaloid synthesis.

Basic Information

Product Name	(6Ar)-5,6,6A,7-Tetrahydro-1,2-Dimethoxy-6-Methyl-4H-Dibenzo[De,G]Quinolin-3-Ol
CAS No.	41645-66-3
Molecular Formula	C20H23NO3
Molecular Weight	325.40 g/mol
Synonyms	1,2-Dimethoxy-6-methylaporphin-3-ol; 3-Hydroxy-1,2-dimethoxy-6-methylaporphine; Glaucine Metabolite; (6aR)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-3-ol; Aporphine alkaloid derivative
EINECS	Contact for details

Quality Control

Our (6Ar)-5,6,6A,7-Tetrahydro-1,2-Dimethoxy-6-Methyl-4H-Dibenzo[De,G]Quinolin-3-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring full traceability and compliance with research-grade material standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.