Description

2,2',4,5'-Tetrachlorobiphenyl is a specific congener of polychlorinated biphenyls (PCBs), a well-studied class of synthetic organic chemicals. This compound is of significant importance for analytical and research purposes, serving as a critical reference standard for environmental monitoring, toxicological studies, and regulatory compliance testing. It is primarily needed by analytical laboratories, environmental testing facilities, and research institutions focused on persistent organic pollutant (POP) analysis, PCB fate and transport studies, and method development.

Application

• Analytical Reference Standard: Primary use as a certified reference material (CRM) for the qualitative and quantitative analysis of PCB mixtures in environmental samples.
• Environmental Monitoring: Calibration and quality control for detecting and quantifying PCB congeners in soil, water, sediment, and air samples to assess contamination levels.
• Toxicological Research: Used in laboratory studies to investigate the specific biological effects, metabolic pathways, and toxicity profiles of individual PCB congeners.
• Method Development & Validation: Essential for developing, optimizing, and validating analytical methods such as GC-MS or GC-ECD for PCB separation and detection.
• Regulatory Compliance Testing: Supports testing to ensure compliance with international regulations (e.g., Stockholm Convention, EPA methods) governing POPs and PCBs.
• Forensic Analysis: Aids in source identification and fingerprinting of PCB contamination by comparing congener patterns.

Basic Information

Product Name	2,2',4,5'-Tetrachlorobiphenyl
CAS No.	41464-40-8
Molecular Formula	C12H6Cl4
Molecular Weight	291.99 g/mol
Synonyms	PCB 49; 2,2',4,5'-Tetrachloro-1,1'-biphenyl; 1,1'-Biphenyl, 2,2',4,5'-tetrachloro-; 2,2',4,5'-Tetrachlorodiphenyl; 2,2',4,5'-TCB; Tetrachlorobiphenyl (2,2',4,5'-); BZ# 49; IUPAC: 1,2,4-Trichloro-5-(2,5-dichlorophenyl)benzene (alternative numbering)
EINECS	Contact for details

Quality Control

Our high-purity 2,2',4,5'-Tetrachlorobiphenyl is manufactured and handled under strict quality protocols to ensure identity, purity, and stability. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing results from advanced chromatographic and spectroscopic analyses. We adhere to relevant guidelines for reference material production to support reliable and reproducible scientific data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. For long-term stability, storage under inert atmosphere is recommended.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to reference spectrum
Identification (GC/MS)	Conforms to reference retention time and mass spectrum
Purity (by GC-FID/GC-ECD)	≥ 98.0% (area percentage)
Related Substances (by GC)	Total other PCB congeners < 2.0%
Solubility	Soluble in common organic solvents (e.g., hexane, acetone, toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.